Characterization of patients with malignant solid lesions of the pancreas using endoscopic ultrasound
Keywords:
malignant solid lesions of the pancreas; endoscopic ultrasoundAbstract
Introduction: Pancreatic tumors are the third cause of digestive death according to health statistics. Endoscopic ultrasound has become a very useful basic tool in the diagnosis and differentiation of pancreatic pathologies.
Objective: To describe the characteristics of malignant solid tumors of the páncreas using endoscopic ultrasound in patients treated at the Institute of Gastroenterology.
Methods: A descriptive, ambispective, cross-sectional, case series observational study was carried out on all patients with a diagnosis of malignant solid lesions of the pancreas by endoscopic ultrasound treated at the Institute of Gastroenterology. Clinical and endoscopic variables of interest were determined in the patients studied.
Results: The study universe consisted of 78 patients with a predominance of males (53.8%), most frequently between 50 and 59 years of age. Most malignant solid lesions of the pancreas were located in the cephalic portion of the organ (64.1%). In most cases the vascular compromiso was at the level of the portal vein in 17 individuals. At the time of diagnosis, pancreatic lesions were staged in advanced stages (T3 – T4) (55 cases).
Conclusion: Male sex predominated between 50 and 59 years old. Most cases presented involvement of the portal vein and the diagnosis was established in advanced stages.
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1. Zhang B, Zhu F, Li P, Yu S, Zhao Y, Li M, Endoscopic ultrasound elastography in the diagnosis of pancreatic masses: A meta-analysis. Pancreatology. 2018;18(7):833-840. DOI: https://doi.org/10.1016/j.pan.2018.07.008.
2. Rawla P, Sunkara, T &Gaduputi, V. Epidemiology of pancreatic cancer: global trends, etiology and risk factors. World J Oncol. 2019;10(1):10-27. DOI: https://doi.org/10.14740/wjon1166.
3. Zhao Z, Liu W. Pancreatic Cancer: A Review of Risk Factors, Diagnosis, and Treatment. Technol Cancer Res Treat. 2020;19:1533033820962117. DOI: https://doi.org/10.1177/1533033820962117.
4. Yousaf MN, Chaudhary FS, Ehsan A, Suarez AL, Muniraj T, Jamidar P et al. Endoscopic ultrasound (EUS) and the management of pancreatic cancer. BMJ Open Gastroenterol. 2020;7(1):e000408. DOI: https://doi.org/10.1136/bmjgast-2020-000408.
5. McGuigan A, Kelly P, Turkington RC, Jones C, Coleman HG, McCain RS. Pancreatic cancer: A review of clinical diagnosis, epidemiology, treatment and outcomes. World J Gastroenterol. 2018;24(43):4846-4861. DOI: https://doi.org/10.3748/wjg.v24.i43.4846.
6. Hu JX, Zhao CF, Chen WB, Liu QC, Li QW, Lin YY, Gao F. Pancreatic cancer: A review of epidemiology, trend, and risk factors. World J Gastroenterol. 2021;27(27):4298-4321. DOI: https://doi.org/10.3748/wjg.v27.i27.4298.
7. Chen W, Zheng R, Baade PD, Zhang S, Zeng H, Bray F, Jemal A, Yu XQ, He J. Cancer statistics in China, 2015. CA Cancer J Clin. 2016;66(2):115-32. DOI: https://doi.org/10.3322/caac.21338.
8. Siegel RL, Miller KD, Fuchs HE, Jemal A. Cancer Statistics, 2021. CA Cancer J Clin. 2021;71(1):7-33. DOI: https://doi.org/10.3322/caac.21654.
9. Valón Costa Oriol, Lubín García Ana, Romaguera Barroso Danilo, Romero García Lázaro Ibrahim. Caracterización clinicoepidemiológica de pacientes con cáncer de páncreas en un servicio de cirugía general. MEDISAN [Internet]. 2022 Ago[acceso: 20/02/2023]; 26(4): e4216.Disponible en: http://scielo.sld.cu/scielo.php?pid=S1029-30192022000400003&script=sci_arttext
10. Lee M, Kwon W, Kim H, Byun Y, Han Y, Kang JS, Choi YJ, Jang JY. The Role of Location of Tumor in the Prognosis of the Pancreatic Cancer. Cancers (Basel). 2020;12(8):2036. DOI: https://doi.org/10.3390/cancers12082036.
11. Takahashi C, Shridhar R, Huston J, Meredith K. Correlation of tumor size and survival in pancreatic cancer. J Gastrointest Oncol. 2018;9(5):910-921. DOI: https://doi.org/10.21037/jgo.2018.08.06.
12. Sánchez García NL, Moure Díaz A, Labrada Moreno LM, Periles Gordillo U, Pérez-Triana F, Hernández Casas Y, Elvirez Gutiérrez Á. Pacientes con tumores malignos del segmento biliopancreático atendidos en el Instituto de Gastroenterología. Archivos Cubanos de Gastroenterología. 2021[acceso: 20/02/2023];2(1):e55.Disponible en: https://revgastro.sld.cu/index.php/gast/article/view/53
13. Li D, Hu B, Zhou Y, Wan T, Si X. Impact of tumor size on survival of patients with resected pancreatic ductal adenocarcinoma: a systematic review and meta-analysis. BMC Cancer. 2018;18(1):985. DOI: https://doi.org/10.1186/s12885-018-4901-9.
14. O’Reilly D, Fou L, Hasler E, Hawkins J, O’Connell S, Pelone F, et al. Diagnosis and management of pancreatic cancer in adults: A summary of guidelines from the UK National Institute for Health and Care Excellence. Pancreatology. 2018;18(8):962-970. DOI: https://doi.org/10.1016/j.pan.2018.09.012.
15. Bispo M, Marques S, Rio-Tinto R., Fidalgo P, DevièreJ. The role of endoscopic ultrasound in pancreatic cancer staging in the Era of neoadjuvant therapy and personalised medicine. GE Port J Gastroenterol. 2021;28(2):111-120. DOI: https://doi.org/10.1159/000509197.
16. Nawaz H, Fan CY, Kloke J, Khalid A, McGrath K, Landsittel D, et al. Performance characteristics of endoscopic ultrasound in the staging of pancreatic cancer: a meta-analysis. JOP. 2013;14(5):484-97. DOI: https://doi.org/10.6092/1590-8577/1512.
17. James PD, Meng ZW, Zhang M, Belletrutti PJ, Mohamed R, Ghali W, et al. The incremental benefit of EUS for identifying unresectable disease among adults with pancreatic adenocarcinoma: A meta-analysis. PLoS One. 2017;12(3):e0173687. DOI: https://doi.org/10.1371/journal.pone.0173687.
18. Zakaria A, Al-Share B, Klapman JB, Dam A. The Role of Endoscopic Ultrasonography in the Diagnosis and Staging of Pancreatic Cancer. Cancers (Basel). 2022;14(6):1373. DOI: 10.3390/cancers14061373.
19. Fujii Y, Matsumoto K, Kato H, Saragai Y, Takada S, Mizukawa S, et al. Diagnostic ability of convex-arrayed endoscopic ultrasonography for major vascular invasion in pancreatic cancer. Clin Endosc. 2019;52(5):479-485. DOI: https://doi.org/10.5946/ce.2018.163.
20. Yin F, Saad M, Xie H, Lin J, Jackson CR, Ren B, et al. Validation of American Joint Committee on Cancer 8th edition of TNM staging in resected distal pancreatic cancer. World J Gastrointest Pharmacol Ther. 2020 9;11(2):25-39. DOI: https://doi.org/10.4292/wjgpt.v11.i2.25.
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